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Nephrology, Rheumatology and Clinical Immunology
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Nephrology, Rheumatology and Clinical Immunology
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Academic year 2023/2024
- Course ID
- SCB0220
- Teachers
- Dario Roccatello (Coordinator)
Savino Sciascia (Lecturer)
Roberta Fenoglio (Lecturer)
Annamaria Iagnocco (Lecturer)
Alessandro Morotti (Lecturer)
Elisa Menegatti (Lecturer) - Year
- 4th year
- Teaching period
- First semester
- Type
- Basic
- Credits/Recognition
- 6 (48 hours of lectures, 24 hours of exercises)
- Course disciplinary sector (SSD)
- INF/01 - informatics
MED/09 - internal medicine
MED/14 - nephrology
MED/16 - rheumatology - Delivery
- Formal authority
- Language
- English
- Attendance
- Mandatory
- Type of examination
- Written and oral
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Sommario del corso
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Course objectives
This course will provide a foundation in knowledge and skills necessary for medical students to recognize the most important medical problems and to construct clinical reasoning models in the field of nephrology, rheumatology and clinical immunology.
Upon successful completion of this course, students will be able to demonstrate the knowledge, attitudes and skills needed to indentify and provide basic care for patients with nephrology, rheumatologic and immunologic diseases.
Students will be able to formulate a differential diagnosis, assessment and a prioritized plan for the standardized patient.- Oggetto:
Results of learning outcomes
Demonstrate knowledge, clinical and technical skills and decision-making capabilities pertinent to the management of patients with medical problems in the field of nephrology, rheumatology and clinical immunology.
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Program
Nephrology
- Assessment of Glomerular Filtration Rate.
- Urinalysis.
- Disorders of Sodium and Potassium Metabolism.
- Approach to Acid-Base Disorders.
- Glomerular Clinicopathologic Syndromes.
- Minimal Change Disease.
- Focal Segmental Glomerulosclerosis.
- Membranous Nephropathy.
- Immunoglobulin A Nephropathy.
- Goodpasture Syndrome and Other Antiglomerular Basement Membrane Diseases.
- Postinfectious Glomerulonephritis.
- Renal involvement in systemic vasculitis (granulomatosis with polyangiitis, microscopic polyangiitis and eosinophilic granulomatosis with polyangiitis).
- Henoch-Schönlein Purpura Nephritis (IgA vasculitis).
- Lupus Nephritis.
- Pathogenesis, Pathophysiology, and Treatment of Diabetic Nephropathy.
- Dysproteinemias related disorders.
- Amyloidosis.
- Thrombotic Microangiopathies and aPL Nephropathy.
- The Kidney in Cancers.
- Acute Kidney Injury.
- Polycystic and Other Cystic Kidney Diseases and Nephronophthisis and Medullary Cystic Kidney Disease.
- Alport Syndrome and Related Disorders.
- Fabry Disease.
- Chronic Tubulointerstitial Disease.
- Nephrolithiasis.
- Urinary Tract Infection and Pyelonephritis.
- Pregnancy in immunomediated and kidney diseases.
- Chronic Kidney Disease and its Therapy.
- Kidney Replacement Therapies: Dialysis and Transplantation.
Rheumatology
- Introductory Aspects of RMDs.
- Inflammatory Arthropathies.
- Rheumatoid arthritis.
- Spondyloarthritis.
- The concept of Spondyloarthritis.
- Ankylosing Spondylitis.
- Psoriatic arthritis.
- Enteropathic arthritis.
- Reactive arthritis.
- Undifferentiated Spondyloarthritis.
- Autoinflammatory Syndromes.
- Familial Mediterrannean Fever.
- Adult Still Disease.
- IGG4-related Disease.
- Connective Tissue Diseases:
- Systemic Lupus Erythematosus;
- Antiphospholipid Syndrome;
- Systemic Sclerosis;
- Sjögren Syndrome;
- Overlap Syndromes;
- Mixed Connective Tissue Disease;
- Undifferentiated Connective Tissue Disease.
- Polymyositis and Dermatomyositis.
- Polymyalgia Rheumatica and Giant Cell Arteritis.
- Vasculitis.
- Giant Cell Arteritis.
- Takayasu’s arteritis.
- Kawasaki Disease.
- Polyarteritis nodosa.
- ANCA-vasculitis.
- Behçet Disease.
Clinical Immunology
- Allergic diseases (including Extrinsic allergic alveolitis).
- Immunodeficiencies.
- Complements defects.
- Phagocyte deficiencies and basophils/eosinophils diseases.
- Sarcoidosis.
- Idiopathic lung fibrosis.
- Oncoimmunology.
- Drug hypersensitivity.
- Glucocorticoids, immunoglobulin-therapy and immunomodulating drugs.
Proteomics and Genomics
- Laboratory assessment of immune-mediated diseases:
- Principles of EIA and IF techniques;
- ANA, anti DNA, ENA, ANCA, Ra Test, Anti-CCP, cryoglobulin detection, Antiphospholipid antibody detection.
- Big data analyses.
- Principles of NGS procedures.
- Genomics and phenotypes.
- Proteomic approches to diagnosis and therapy.
- Mosaics in Autoimmunity (Yehuda Shoenfeld lectures).
- Immune-neurological diseases.
- ASIA syndrome and Sylicosis.
- Sclerodermic disorders.
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Course delivery
Lectures in presence, supported/supplemented by recorded lectures that the students can access online through the platform Moodle
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Learning assessment methods
The exam test covers all the disciplines included in the course and the final score proportionally takes into account results of each module.
EXAMINATION ARRANGEMENTS: written and oral.
- WRITTEN:
- MED/05 - Clinical Pathology;
- MED/09 - Internal Medicine;
- MED/15 – Rheumatology.
- ORAL:
- MED/14 – Nephrology.
- Proteomics exam: 20 questions, brief open answers, 30 min time. No penalties for incorrect answers.
- Immunology exam: Multiple choice test. 31 questions. 20 min time. No penalties for incorrect answers.
- Rheumatology exam: Multiple choice test. 31 questions. 20 min time. No penalties for incorrect answers.
- Nephrology exam: oral exam.
Partial scores kept valid until the next exam.Final evaluation of the course will be the result of the weighted average of the scores of the single modules.
MED/05 - Clinical Pathology (1 CFU)
MED/09 - Internal Medicine (1 CFU)
MED/14 – Nephrology (3 CFU)
MED/15 – Rheumatology (1 CFU)
Professors are available upon mail contact.
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Suggested readings and bibliography
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- Book
- Title:
- Clinical Immunology: Principles and Practice
- Year of publication:
- 2019
- Publisher:
- Elsevier
- Author:
- Robert R. Rich (ed.)
- ISBN
- Permalink:
- Required:
- Yes
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- Book
- Title:
- Harrison's Principles of Internal Medicine, 20e
- Year of publication:
- 2018
- Publisher:
- McGraw-Hill
- Author:
- J. Larry Jameson, Anthony S. Fauci, Dennis L. Kasper, Stephen L. Hauser, Dan L. Longo, Joseph Loscalzo
- ISBN
- Permalink:
- Required:
- Yes
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- Book
- Title:
- EULAR Textbook of Rheumatology
- Year of publication:
- 2018
- Publisher:
- EULAR
- Author:
- EULAR
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- Required:
- Yes
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- Book
- Title:
- Laposata's Laboratory Medicine: Diagnosis of Disease in the Clinical Laboratory, 3e
- Year of publication:
- 2018
- Publisher:
- McGraw-Hill
- Author:
- Michael Laposata
- ISBN
- Permalink:
- Required:
- Yes
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- Book
- Title:
- Immunoassay
- Year of publication:
- 1996
- Publisher:
- Elsevier
- Author:
- Eleftherios P. Diamandis, Theodore K. Christopoulos
- ISBN
- Permalink:
- Required:
- Yes
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- Book
- Title:
- Current Diagnosis & Treatment: Nephrology & Hypertension
- Year of publication:
- 2018
- Publisher:
- McGraw Hill
- Author:
- Edgar V. Lerma, Mitchell H. Rosner, Mark A. Perazella
- ISBN
- Permalink:
- Required:
- Yes
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- Book
- Title:
- Oxford Textbook of Clinical Nephrology: Three-Volume Pack (4 edn)
- Year of publication:
- 2019
- Publisher:
- Oxford University Press
- Author:
- Neil N. Turner (ed.), Neil N. Turner (ed.), Norbert Lameire (ed.), David J. Goldsmith (ed.), Christopher G. Winearls (ed.), Jonathan Himmelfarb (ed.), Giuseppe Remuzzi (ed.)
- ISBN
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- Required:
- Yes
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Notes
Students with DSA or disabilities are kindly requested to take note of the reception services and support services offered by the University of Turin, and in particular of the procedures required for exam support.
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Teaching Modules
- Nephrology, Rheumatology and Clinical Immunology - Module of Clinical Immunology (SCB0220C)
- Nephrology, Rheumatology and Clinical Immunology - Module of Nephrology (SCB0220A)
- Nephrology, Rheumatology and Clinical Immunology - Module of Proteomics and Genomics (SCB0220D)
- Nephrology, Rheumatology and Clinical Immunology - Module of Rheumatology (SCB0220B)
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