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Microbiology
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Microbiology
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Academic year 2020/2021
- Course ID
- SCB0204
- Teaching staff
- Prof. David Lembo (Coordinator)
Prof.ssa Manuela Donalisio (Lecturer)
Dott. Andrea Civra (Lecturer) - Year
- 2nd year
- Teaching period
- First semester
- Type
- Basic
- Credits/Recognition
- 7
- Course disciplinary sector (SSD)
- MED/07 - microbiologia e microbiologia clinica
- Delivery
- E-learning
- Language
- English
- Attendance
- Mandatory
- Type of examination
- Oral
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Sommario del corso
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Course objectives
This course covers principles of medical microbiology with emphasis to microorganisms (bacteria, viruses, fungi and protozoa) and human infectious disease. Topics include an overview of microbial structures and virulence factors, the host-parasite interactions, the pathogenic mechanisms of the most important infectious diseases, the principal concepts regarding sterilization, microbiological diagnosis, antibiotic and antiviral therapy, the conditions promoting the rise up of infections and the prevention options.
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Results of learning outcomes
By the end of this course, the student will have acquired basic knowledge of pathogenesis of microbial and virus infections to be able to implement a rational approach to the diagnosis and treatment of infectious diseases. The student shall learn the basic knowledge in the following topics:
- General features of bacteriology, virology, mycology and parasitology
- Pathogenicity, virulence, and epidemiology
- Disease transmission and physical and chemical microbial control
- Microbiological diagnostic techniques
- Antimicrobial therapy
- Common bacterial, fungal, protozoa and viral diseases
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Course delivery
The Microbiology course will be taught online, mainly in an asynchronous way. Slides with audiocomments for each lesson will be available on Moodle (https://elearning.unito.it/medicina/enrol/index.php?id=3372) according to the timetable of the lessons. We will provide you self-assessment exercises at the end of each teaching module along with commented answers from the lecturers.
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Learning assessment methods
Exams will take place as oral examinations via Webex.
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Support activities
Students with disorders that may affect learning (e.g. color blind students, visually impaired, hearing impaired, dyslexic or with physical disabilities) are encouraged to contact the lecturers to adapt learning materials, activities and testing methods.
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Program
- Introduction to Medical Microbiology:
- History of microbiology
- Koch's postulates
- Classification of microbes
- General Bacteriology:
- Structure
- Endospore
- Human microbiome and concept of opportunism
- Virulence factors
- Microbial growth
- Bacterial genetics
- Laboratory diagnosis of bacterial diseases
- Methods of Sterilization
- Antibiotics
- Systematic Bacteriology:
- Staphylococcus
- Streptococcus
- Bacillus
- Listeria
- Mycobacterium
- Neisseria
- Haemophilus
- Legionella
- Enterobacteriaceae
- Yersinia
- Vibrio
- Pseudomonas
- Campylobacter and Helicobacter
- Clostridium
- Spirochetes (Treponema, Borrelia, Leptospira)
- Brucella
- Mycoplasma and Ureaplasma
- Rickettsia, Ehrlichia
- Clamydia
- Bordetella
- Mycology:
- Structure, replication, pathogenesis, laboratory diagnosis of fungal disease and antifungal agents
- Superficial, cutaneous, subcutaneous and systemic mycoses
- Opportunistic mycoses (Candida, Criptococcus, Aspergillus and Pneumocystis)
- Parasitology:
- Parasitic classification, structure, replication, pathogenesis of parasitic diseases, laboratory diagnosis and antiparasitic agents
- Intestinal protozoa (Giardia, Cryptosporidium, Entamoeba)
- Urogenital protozoa (Trichomonas)
- Blood and tissue protozoa (Plasmodium, Toxoplasma, Leishmania, Trypanosoma)
- Main concepts on infections by common nematodes, trematodes and cestodes
- General virology:
- Structure
- Classification
- Replication mechanisms
- Laboratory diagnosis of viral diseases
- Antiviral chemotherapy
- Systematic virology:
- Herpesviruses
- Papillomaviruses and Polyomaviruses
- Adenoviruses
- Poxviruses
- Parvoviruses
- Paramyxoviruses
- Rhabdoviruses
- Arenaviruses and Bunyaviruses
- Orthomyxoviruses
- Retroviruses
- Reoviruses
- Caliciviruses
- Togaviruses
- Picornaviruses
- Hepatitis Viruses
- Flaviviruses
- Coronaviruses
- Filoviruses
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Suggested readings and bibliography
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You can access freely to the following online textbooks that we recommend:
- Jawetz, Ernest Jawetz Melnick & Adelbergs Medical Microbiology McGraw-Hill 2019
http://bibliopass.unito.it/login?url=https://accessmedicine.mhmedical.com/book.aspx?bookid=2629 - Kenneth J Ryan Sherris Medical Microbiology, 7e McGraw-Hill 2018
http://bibliopass.unito.it/login?url=https://accessmedicine.mhmedical.com/book.aspx?bookid=2268
- Jawetz, Ernest Jawetz Melnick & Adelbergs Medical Microbiology McGraw-Hill 2019
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Note
Despite the on-line format, active learning is expected: students should engage with the material, answer the exercise questions and contact us (david.lembo@unito.it; manuela.donalisio@unito.it; andrea.civra@unito.it) if in doubt or in need of further explanation.
Webex meetings will be organized in our virtual rooms (https://unito.webex.com/meet/david.lembo; https://unito.webex.com/meet/manuela.donalisio; https://unito.webex.com/meet/andrea.civra) to answer any doubts and provide the required explanations.
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