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Nephrology, rheumatology and clinical immunology - Module of Proteomics and Genomics

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Nephrology, rheumatology and clinical immunology - Module of Proteomics and Genomics

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Academic year 2022/2023

Course ID
SCB0220D
Teacher
Elisa Menegatti (Lecturer)
Modular course
Year
4th year
Teaching period
First semester
Type
Basic
Credits/Recognition
1 (8 hours of lectures, 4 hours of exercises)
Course disciplinary sector (SSD)
INF/01 - informatics
Delivery
Formal authority
Language
English
Attendance
Mandatory
Type of examination
Written and oral
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Sommario del corso

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Course objectives

This module will provide a foundation in knowledge and skills necessary for medical students to recognize the most important medical problems and to construct clinical reasoning models in the field of proteomics and genomics.

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Results of learning outcomes

emonstrate knowledge, clinical and technical skills and decision-making capabilities pertinent to the management of patients with medical problems in the field of protemics and genomics

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Course delivery

Lectures in presence, supported/ supplemented by recorded lectures that the students can access online through the platform Moodle

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Learning assessment methods

  • Proteomics exam: 20 questions, brief open answers, 30 min time. No penalties for incorrect answers.
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Program

  • Laboratory assessment of immune-mediated diseases:
    • Principles of EIA and IF techniques;
    • ANA, anti DNA, ENA, ANCA, Ra Test, Anti-CCP, cryoglobulin detection, Antiphospholipid antibody detection.
  • Big data analyses.
  • Principles of NGS procedures.
  • Genomics and phenotypes.
  • Proteomic approches to diagnosis and therapy.
  • Mosaics in Autoimmunity (Yehuda Shoenfeld lectures).
  • Immune-neurological diseases.
  • ASIA syndrome and Sylicosis.
  • Sclerodermic disorders.

Suggested readings and bibliography



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Book
Title:  
Laposata's Laboratory Medicine: Diagnosis of Disease in the Clinical Laboratory, 3e
Year of publication:  
2018
Publisher:  
McGraw-Hill
Author:  
Michael Laposata
ISBN  
Permalink:  
Required:  
Yes


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Book
Title:  
Immunoassay
Year of publication:  
1996
Publisher:  
Elsevier
Author:  
Eleftherios P. Diamandis, Theodore K. Christopoulos
ISBN  
Permalink:  
Required:  
Yes


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