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Pathology
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Pathology
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Academic year 2022/2023
- Course ID
- SCB0216
- Teaching staff
- Marco Volante (Coordinator)
Luisella Righi (Lecturer)
Anna Sapino (Lecturer) - Year
- 4th year
- Teaching period
- First and Second semester
- Type
- Basic
- Credits/Recognition
- 12 (96 hours of lectures, 48 hours of exercises)
- Course disciplinary sector (SSD)
- MED/08 - pathology
- Delivery
- Formal authority
- Language
- English
- Attendance
- Mandatory
- Type of examination
- Written and oral
- Prerequisites
- Prerequisites are knowledge in normal Anatomy, Histology, Basic Pathology and Immunology, Pathology and Pathophysiology, Cell Biology and Genetics.
- Propedeutic for
- Pathology is propaedeutic for each specialty of medicine (including internal medicine) and surgery, and for Forensic and Occupational Medicine.
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Sommario del corso
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Course objectives
- Basic pathology lesions including cell damage, tissue damage, organ damage. Their evolution during major diseases in different organs and systems.
- Role of pathology in the decision-making process of physicians and surgeons. Making use of diagnostic histopathology and cytopathology for the purposes of diagnosis, preventive medicine, prognosis and treatment of individual patients.
- Role of pathology in understanding how the most relevant diseases of organs and systems work (see syllabus for details).
- Critical analysis when correlating functional changes, signs and symptoms and pathological conditions. Critical ability to interpret underlying mechanisms and understanding clinical significance.
- New molecular diagnostic techniques applied to cells and tissues for diagnostic, prognostic and therapeutic purposes, aimed at better pinpointing human cancers.
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Results of learning outcomes
Learning outcomes include skills and knowledge of protocols and procedures in diagnostic pathology; knowledge of the classification of both non-neoplastic and neoplastic disease for each individual organ and system; applicability and limitations of different types of tissue samples according to the diagnostic context.
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Course delivery
The course consists of face-to-face lectures, integrated lecture, elective teaching activities and case discussions to improve your problem-solving ability. The material from the lectures is made available to the students at the end of each lecture. Web-based lectures will be held on Webex:
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Learning assessment methods
Final examination at the end of the course (no mid-term exams).
The examination is made up of a written test and oral examination. The written test consists of multiple-choice or short-text questions. If successful (i.e., pass mark of 15/30), the student will proceed to the oral examination. The oral examination will account for +/-30% of the mark obtained in the written test. However, in the event of a completely inadequate oral examination, a fail mark will be awarded, regardless of the mark obtained in the written test.
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Support activities
Course lecturers are available upon request to provide students with further information and learning support.
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Program
INTRODUCTION TO PATHOLOGY
- History of pathology; pathology techniques; types of cell and tissue samples, fixation.
CARDIOVASCULAR PATHOLOGY
- Pericardium: effusions, pericarditis, tumours.
- Heart: congenital heart disease; myocarditis; endocarditis; rheumatic heart disease; valve disease; cardiomyopathy; infarction; angina; sudden death.
- Blood vessels: atherosclerosis, calcific sclerosis, arteriolosclerosis; aortic dissection; vasculitis.
- Complex diseases: heart failure; hypertensive disease; heart transplantation.
PULMONARY PATHOLOGY
- Larynx: laryngitis, polyps, papilloma, leukoplakia, carcinoma.
- Lung: cysts; atelectasis, diffuse alveolar damage; pulmonary hypertension; embolism; chronic bronchitis and small airways disease, emphysema, bronchiectasis, asthma; pneumonia; abscess; pulmonary fibrosis, pneumoconiosis, sarcoidosis; tuberculosis; mycosis; lung cancer.
- Pleura: effusions; pleurisy; hyaline plaques; tumours.
- Complex diseases: obstructive and restrictive respiratory syndromes.
MEDIASTINUM
- Tumours (thymic and extrathymic ones).
GASTROINTESTINAL PATHOLOGY
- Oral cavity and salivary glands: inflammatory lesions; precancerous lesions; tumours.
- Esophagus: congenital malformations and stenosis, precancerous lesions and carcinoma.
- Stomach: gastritis; peptic ulcer; polyps and adenoma; carcinoma; other tumors.
- Bowel: congenital abnormalities; diverticular disease; malabsorption; infarction and ischemic colitis; enteritis; inflammatory bowel disease (IBD); polyp, adenoma and adenomatous syndromes; carcinoma and other tumors.
- Peritoneum. Effusions; peritonitis, tumors.
- Liver and biliary tract: vascular diseases; toxic and viral hepatitis; liver necrosis; infections; cholangitis; lithiasis; cirrhosis; primary and secondary tumors.
- Exocrine pancreas: acute and chronic pancreatitis; tumors.
- Complex diseases: liver failure; liver transplant.
BREAST PATHOLOGY
- Mastitis; fibrocystic disease; gynecomastia; fibro-epithelial lesions; papillomas; pre-invasive neoplastic lesions, carcinoma; other tumors.
GENITOURINARY PATHOLOGY
- Kidney: cystic disease; primary and secondary glomerulopathies; primary and secondary tubular diseases; interstitial nephritis; infections; vasculitis; tumors; renal transplant.
- Bladder: cystitis; tumors.
- Testis: orchitis and epididymitis; cryptorchidism; male infertility; tumors.
- Prostate: hyperplasia; inflammation; preinvasive lesions and carcinoma.
- Ovary: physiological changes; cysts and polycystic ovary syndrome; neoplasms
- Uterus: endometrial and cervical infections; endometrial hormonal abnormalities; endometriosis; endometrial hyperplasia; pre-invasive endometrial lesions; endometrial carcinoma; stromal tumors; cervical cancer screening; pre-invasive cervical lesions; cervical carcinoma; pathology of pregnancy.
- Vulva and vagina: inflammatory disorders/infections; tumors.
ENDOCRINE PATHOLOGY
- Thyroid: developmental anomalies; hyperplastic disease; inflammatory-autoimmune diseases; neoplasms; cytology of thyroid nodules.
- Parathyroid: cysts; hyperplasia; tumors.
- Neuroendocrine neoplasms: classification and site-specific characterization.
- Adrenal: congenital anomalies; hemorrhage; infections; hyperplasia; cortical tumors; medullary tumors.
- Pituitary: inflammatory/infiltrative diseases; necrosis; tumors.
HEMATO PATHOLOGY
- Lymph nodes: Lymphoadenitis; Hodgkin and non-Hodgkin lymphomas.
- Bone marrow: leukemias; myeloma; myeloproliferative and myelodisplastic syndromes.
- Spleen: congestion; infarction, splenomegalies, infections.
DERMATO PATHOLOGY
- Inflammatory disorders; infections/infestations; epithelial neoplasms; melanocytic neoplasms; other tumors
NEUROPATHOLOGY:
- Trauma and haemorrhage; infections; demyelinating disorders; degenerative diseases; tumours.
BONE AND SOFT TISSUE PATHOLOGY
- Bone: fibrous dysplasia; osteopenic diseases; Paget's disease; infections; bone tumours.
- Soft tissue: classification of benign tumours and sarcomas.
AUTOPSY
- medical purposes; post-mortem phenomena; definition of cause of death.
Suggested readings and bibliography
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- Book
- Title:
- The Washington Manual of Surgical Pathology
- Year of publication:
- 2019
- Publisher:
- LWW
- Author:
- John D Pfeifer, Louis P Dehner, Peter A Humphrey
- ISBN
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- Required:
- Yes
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- Book
- Title:
- Robbins e Cotran Le basi patologiche delle malattie
- Year of publication:
- 2015
- Publisher:
- Edra Masson
- Author:
- V. Kumar, A. K. Abbas, J. C. Aster
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- Notes:
- Required:
- Yes
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Moduli didattici
- Pathology - Module of Pathology A (SCB0216A)
- Pathology - Module of Pathology B (SCB0216B)
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